Anti-WASL Antibody

Raised against the Wiskott-Aldrich Syndrome-Like (WASL/N-WASP) protein, this rabbit polyclonal primary antibody from Antibodies.com targets a key regulator of Arp2/3-mediated actin polymerization and cytoskeletal remodeling in hematopoietic and neural cells. Supplied as 100 µl of unconjugated IgG, the reagent is validated for Western Blot detection of endogenous WASL in mouse and rat sample lysates.

WASL coordinates signal transduction downstream of Cdc42 and phosphatidylinositol 4,5-bisphosphate (PIP2), making this reagent useful for studies of cell motility, immune synapse formation, endocytosis, and platelet function. Researchers investigating Wiskott-Aldrich Syndrome-related pathways, dendritic spine dynamics, or pathogen motility in host cells can apply the antibody to characterize WASL expression patterns across tissues such as spleen, thymus, and brain.

For optimal results, store refrigerated and protect from light; aliquot upon first use to preserve antibody titer through limited freeze-thaw cycles. The polyclonal format offers broader epitope coverage than monoclonal alternatives, supporting detection of multiple WASL isoforms where Western Blot band patterns may vary by tissue or developmental stage.