Anti-VPS37A Antibody

Affinity-purified polyclonal antibody raised in Rabbit against the human VPS37A target, supplied by Antibodies.com as an unconjugated 100 µl volume. The reagent is validated for western blot and immunohistochemistry applications on human samples, with no conjugated reporter attached.

VPS37A functions as a component of the ESCRT-I complex, participating in multivesicular body formation, ubiquitin-mediated cargo recognition, and endosomal membrane remodeling. Mutations in the VPS37A gene have been linked to hereditary spastic paraplegia type 53, and the protein is studied in the broader context of intracellular trafficking and neurodegeneration.

Storage guidance for this liquid preparation includes refrigerated short-term handling and aliquoting to limit repeated freeze-thaw cycles. The unconjugated format allows researchers to pair the reagent with their preferred HRP, biotin, or fluorophore label for chromogenic or fluorescence-based detection in immunostaining and immunoblotting pipelines.