Anti-VPS28 Antibody

Directed against the vacuolar protein sorting 28 homolog (VPS28), this unconjugated rabbit polyclonal antibody from Antibodies.com is supplied as 100 µl of antisera and is validated for western blot and immunohistochemistry on human samples. VPS28 is a core component of the ESCRT-I complex that recognizes ubiquitinated cargo and drives its sorting into multivesicular bodies, and the reagent is widely used to study endosomal trafficking, retroviral budding, cytokinesis, and autophagy-related membrane remodeling. The polyclonal format provides multi-epitope coverage of the human target, which improves detection on fixed tissue sections and in denaturing immunoblot conditions where single-clone reagents can fail. Researchers commonly deploy it to track ESCRT-I recruitment to endosomal membranes, monitor VPS28 redistribution following cellular stress or viral infection, and probe interactions with binding partners such as TSG101 and VPS37 family proteins. Compatible with standard HRP- and fluorophore-conjugated secondary reagents, the antibody drops into routine immunoblotting, immunofluorescence, and chromogenic IHC pipelines without specialized buffers, and it is intended for research use only.