Anti-VPS26A Antibody

This polyclonal antibody from Antibodies.com targets VPS26A, a core subunit of the retromer complex that mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network. Raised in rabbit, the reagent is supplied as 100 µL of unconjugated antiserum validated for Western blot and immunohistochemistry on human samples. VPS26A functions alongside VPS35 and VPS29 to sort transmembrane receptors, including the cation-independent mannose-6-phosphate receptor, and has been implicated in neurodegenerative disease research, particularly studies of Parkinson and Alzheimer pathology. Investigators studying endosomal trafficking, lysosomal biogenesis, or retromer-mediated cargo recognition use this reagent to probe VPS26A expression in cell lysates and fixed tissue sections. The unconjugated format allows flexible downstream labeling with fluorophore or enzyme conjugates of the researcher's choice, supporting both chromogenic and immunofluorescence detection workflows.