Anti-Vps20-associated 1 homolog Antibody

This rabbit polyclonal antibody from Antibodies.com targets Vps20-associated 1 homolog, the human ESCRT-III subunit also referred to as CHMP6. Supplied as an unconjugated reagent in a 100 µl liquid format, the antibody is validated for western blot, immunohistochemistry, and immunofluorescence on human specimens, enabling studies of multivesicular body formation, membrane scission, late endosomal sorting, and abscission during cytokinesis.

Vps20-associated 1 homolog functions within the endosomal sorting complexes required for transport machinery, where it assembles into helical filaments that constrict and sever membranes. The polyclonal host rabbit format offers recognition of multiple epitopes across the protein, useful when investigating the subunit's recruitment to endosomal membranes and midbodies. Reactivity is reported specifically for human samples, supporting cell line and tissue-based experiments probing ESCRT-dependent trafficking.

For handling, aliquot upon first thaw and store refrigerated at 2 to 8 degrees C, avoiding repeated freeze-thaw cycles to preserve antibody titer over the shelf life of the reagent. Intended for research use only and not for diagnostic or therapeutic applications.