Anti-Vitronectin Antibody

This unconjugated rabbit polyclonal reagent from Antibodies.com targets human vitronectin, a multifunctional glycoprotein circulating in plasma and deposited into extracellular matrices. Provided at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the antibody is supplied as a 100 µl vial and validated for western blot and immunohistochemistry workflows.

Vitronectin mediates cell attachment and spreading through integrin αvβ3 engagement and acts as a carrier for plasminogen activator inhibitor-1, linking it to fibrinolysis and complement regulation. Researchers investigating hepatocellular carcinoma, glomerular injury, age-related macular degeneration, and biomaterial coatings for regenerative medicine commonly select this reagent. The polyclonal format enables recognition of multiple epitopes on native and recombinant protein, supporting reproducible detection in tissue sections and immunoblots of human cell lysates.

Handle the vial refrigerated; for extended projects, aliquot and freeze at -20 °C to limit freeze-thaw cycles and preserve antibody activity across many months.