Anti-Vinculin Antibody

Antibodies.com offers this rabbit-derived polyclonal reagent targeting vinculin, a 124 kDa membrane-cytoskeletal protein concentrated at focal adhesions and adherens junctions, where it links the actin cytoskeleton to the cell membrane and transmits mechanical force between the cell and the extracellular matrix.

The unconjugated preparation is supplied in a 100 µl vial and has been validated for Western blot, immunohistochemistry, immunofluorescence, and ELISA workflows. It detects vinculin in human, mouse, and rat samples, supporting research into cell adhesion, migration, cytoskeletal remodeling, and mechanotransduction across normal and disease-state tissues.

For handling, aliquot upon arrival and store at -20 °C, protecting from light and limiting freeze-thaw cycles by preparing single-use aliquots. Intended for research use only in vitro, this reagent is well suited to studies of focal adhesion dynamics, cell junction integrity, and cytoskeletal organization in cancer, cardiovascular, and stem cell research applications.