Anti-VGLL2 Antibody

This rabbit polyclonal reagent from Antibodies.com targets VGLL2 (vestigial-like 2, also known as Tondu), a transcriptional cofactor that binds TEAD1-4 factors and modulates skeletal muscle gene expression. Expressed predominantly in striated muscle, VGLL2 plays documented roles in myocyte differentiation, muscle fiber type specification, and hypertrophic signaling downstream of Hippo pathway cues. The unconjugated antibody is supplied at 1 mg/ml in phosphate buffered saline containing 0.05% sodium azide as a microbial preservative, with a standard working aliquot drawn from each 100 µl vial. Validation work covers western blot reactivity on human, mouse, and rat samples, making the reagent useful for cross-species comparisons of muscle lysates, myoblast cultures, and tissue biopsies. Researchers investigating TEAD-VGLL2 complexes, rhabdomyosarcoma models, and exercise-induced muscle adaptations turn to this antibody to probe endogenous protein abundance and to compare normal versus regenerating or diseased muscle. Refrigerate at standard cold-storage temperatures and protect from light to preserve conjugate integrity; sodium azide handling precautions apply during downstream conjugation steps.