Anti-VEGFR2/Flk-1 (phospho-Y1175) Antibody

This phospho-specific polyclonal reagent from Antibodies.com selectively recognizes vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR or Flk-1) when phosphorylated at the key tyrosine 1175 autophosphorylation site. Raised in rabbit and supplied as an unconjugated 100 µl vial at 1 mg/ml in phosphate buffered saline containing 0.05% sodium azide (pH approximately 7.2), the antibody is validated for immunohistochemistry on formalin-fixed tissue sections prepared from human, mouse, and rat samples. Because Y1175 phosphorylation drives VEGF-mediated downstream signaling through PLCγ and MAPK cascades, this reagent is widely used to map receptor activation in tumor angiogenesis studies, endothelial cell biology, and vascular development research. Store at 4 °C; aliquotting is recommended to limit freeze-thaw cycles and preserve phospho-epitope recognition across the working shelf life.