Anti-VEGFR2/Flk-1 (I1181) Antibody

VEGFR2 (vascular endothelial growth factor receptor 2), also called Flk-1 in rodent systems or KDR in human cells, is a type I transmembrane receptor tyrosine kinase that mediates VEGF-A signaling and contributes to vasculogenesis, angiogenic sprouting, and endothelial cell survival. This rabbit polyclonal primary antibody from Antibodies.com is unconjugated and supplied at 1 mg/ml in phosphate-buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2. The reagent is validated for immunohistochemistry (IHC) and cross-reacts with the receptor in human, mouse, and rat samples, reflecting conservation of the antigenic region across these species. Each vial contains 100 µl of antibody at the supplied concentration, sufficient for multiple staining runs when titrated against the user's own tissue preparation and detection system. For short-term storage, keep the vial refrigerated at 4°C; for longer-term storage, aliquot and freeze at -20°C or below, and avoid repeated freeze-thaw cycles to preserve activity. Sodium azide is present as a microbial preservative, so the product is not appropriate for protocols that require azide-free conditions. Researchers studying tumor angiogenesis, vascular development, endothelial cell biology, or VEGF-pathway therapeutics commonly use such reagents to map receptor expression patterns in clinical and preclinical tissue samples.