Anti-VDR Antibody

This rabbit polyclonal antibody targets the Vitamin D Receptor (VDR), a nuclear transcription factor that mediates the genomic actions of 1,25-dihydroxyvitamin D3 in calcium homeostasis, bone metabolism, and immune regulation.

Produced by Antibodies.com, the reagent is supplied as a 100 µl liquid aliquot of unconjugated IgG raised in rabbit and validated for Western blot (WB) and immunofluorescence (IF) applications. Cross-reactivity is reported with human, mouse, and rat samples, making it suitable for comparative studies of vitamin D signaling across standard laboratory models.

The polyclonal format increases the likelihood of recognizing multiple epitopes on the VDR protein, which can improve signal detection in WB membranes and IF-stained cell preparations. Refrigerated storage helps preserve antibody activity for repeated experiments, with aliquoting advised to limit freeze-thaw cycles of the stock solution.

Researchers investigating VDR expression in intestinal, renal, skeletal, or immune cell contexts commonly use this reagent in panels targeting nuclear hormone receptors, often alongside antibodies against downstream effectors in vitamin D pathway research.