Anti-VDAC1 Antibody

This rabbit polyclonal reagent targets voltage-dependent anion channel 1 (VDAC1), a porin protein embedded in the mitochondrial outer membrane. VDAC1 governs the flux of ATP, ADP, pyruvate, malate, and other metabolites between the cytosol and the mitochondrial intermembrane space, and it interfaces with pathways controlling apoptosis, calcium homeostasis, and reactive oxygen species exchange. Investigators working on mitochondrial bioenergetics, neurodegeneration, ischemic injury, and tumor metabolism rely on VDAC1 detection to confirm mitochondrial localization and to normalize mitochondrial-enriched fractions as a loading reference.

Provided at 1 mg/mL in PBS with 0.1% sodium azide and 50% glycerol, this unconjugated polyclonal reagent from Antibodies.com is supplied as a 100 µL vial that supports multiple western blot, immunohistochemistry, and immunofluorescence experiments. Reactivity has been characterized on human, mouse, and rat samples, enabling use across cell culture models and tissue sections from these species. The 50% glycerol cryoprotectant allows storage at -20 °C and limits freeze-thaw damage, while the sodium azide component stabilizes working aliquots kept under refrigerated conditions.