Anti-VCAM1 Antibody [Assigned #A11236]

For researchers probing inflammatory cell recruitment at the vascular wall, this unconjugated IgG reagent from Antibodies.com targets the type I transmembrane glycoprotein VCAM1 (CD106), enabling detection of cytokine-induced endothelial activation in human, mouse, and rat samples. Validated for western blot, immunohistochemistry, immunofluorescence, and immunoprecipitation, the rabbit monoclonal clone is supplied as a 200 µl liquid aliquot and pairs cleanly with user-selected fluorophore or HRP secondary reagents for imaging or immunoblotting workflows. Published applications include probing VCAM1 upregulation in endothelial injury models at working dilutions around 1:1000. The 81 kDa adhesion molecule functions as a leukocyte counter-receptor for α4 integrins on inflamed endothelium, making the antibody a useful marker for studies of atherosclerosis, transplant rejection, autoimmune inflammation, and tumor cell extravasation. Store at -20 °C in working aliquots to preserve reactivity; limit repeated freeze-thaw cycles on the stock vial.