Anti-VAV1 (Ab-174) Antibody

Manufactured by Antibodies.com, the VAV1 (Ab-174) polyclonal antiserum is raised in rabbit and affinity-purified from rabbit antiserum by affinity chromatography against an epitope-specific immunogen — a synthesized non-phosphopeptide derived from human VAV1 around the phosphorylation site of tyrosine 174 (E-I-Y-E-D). The reagent detects endogenous levels of total VAV1 protein (synonyms: Proto-oncogene vav, VAV) and is supplied as a 50 µL aliquot at 1.0 mg/mL in phosphate-buffered saline (without Mg²⁺ and Ca²⁺), pH 7.4, with 150 mM NaCl, 0.02% sodium azide and 50% glycerol. The host is Rabbit, clonality is Polyclonal, isotype is Rabbit IgG, and the antibody is Unconjugated, making it suitable for standard detection chemistries. Validated applications are Western blot (WB) and immunohistochemistry (IHC), with reactivity confirmed against Human samples. The product is dispatched from Cambridge (UK) with a typical lead time of 6–9 business days and should be shipped at 4 °C; upon receipt it should be aliquoted and stored at –20 °C, avoiding repeated freeze/thaw cycles to preserve activity. Intended for research use only and not for diagnostic or therapeutic applications, this reagent offers a reliable tool for probing VAV1 expression in signaling and oncogenesis studies.