Anti-VAV1 (Ab-174) Antibody

This polyclonal reagent from Antibodies.com targets VAV1, a hematopoietic-specific guanine nucleotide exchange factor that couples immune receptor activation to Rho/Rac GTPase signaling. VAV1 is essential for T-cell and B-cell receptor-driven responses, cytoskeletal remodeling, and lymphocyte development, and it has become a focus of investigation in hematopoietic malignancies and immune signaling research.

Raised in rabbit and supplied as 100 µl of unconjugated antiserum, the antibody is validated for Western blot and immunohistochemistry on human specimens. Its polyclonal format supports recognition of multiple epitopes across the VAV1 protein, giving researchers consistent detection on western blot membranes and on formalin-fixed paraffin-embedded lymphoid tissue sections used in studies of receptor-mediated signal transduction and leukemia biology.