Anti-VASP Antibody

VASP (Vasodilator-Stimulated Phosphoprotein) is an actin-associated regulatory protein central to cytoskeletal dynamics, focal adhesion turnover, cell motility, and platelet aggregation, where its phosphorylation status serves as a classical biochemical readout for cAMP- and cGMP-dependent kinase (PKA/PKG) signaling. This unconjugated rabbit polyclonal reagent enables multi-format detection of endogenous VASP across a broad reactivity panel that includes human, mouse, rat, and monkey samples, making it useful for cardiovascular, megakaryocyte, and leukocyte migration studies where cross-species comparison is required.

Validated for Western blot, immunohistochemistry, immunofluorescence, and ELISA workflows, the antibody supports routine protein-level confirmation, spatial localization in fixed tissue, subcellular imaging, and quantitative antigen detection. Each vial supplies 100 µL of polyclonal antiserum, a format that allows flexible dilution across blotting and staining protocols while accommodating multiple replicate experiments. Researchers commonly apply this reagent to probe VASP phosphorylation at Ser157 and Ser239, examine Ena/VASP family function at the leading edge during cell migration, and characterize platelet activation responses in translational models of vascular and thrombotic disease.

Supplied by Antibodies.com, the antibody is intended for research use only and is stored under standard refrigerated conditions to preserve polyclonal reactivity over its working shelf life. The unconjugated format gives laboratories freedom to pair the reagent with HRP, fluorophore, or biotin secondary detection systems tailored to individual assay designs.