Anti-Varicella-Zoster Virus (VZV-gE) Antibody

Varicella-zoster virus (VZV) glycoprotein E (gE) is among the most immunogenic envelope proteins produced during VZV infection, making it a principal target for antibody-based detection of viral replication and latency studies.

This unconjugated mouse monoclonal antibody, distributed by Antibodies.com, is supplied as a purified 100 µg vial for use in ELISA, western blot (WB), and immunofluorescence assay (IFA) workflows. The IgG1(k) isotype provides a well-characterized reagent backbone for direct and indirect detection strategies.

Glycoprotein E mediates VZV cell-to-cell spread across epithelia and neurons and is the recombinant antigen incorporated into the adjuvanted shingles vaccine, so high-affinity monoclonals against this target support vaccine development, seroepidemiology, and reactivation research.

Anti-gE clones are routinely applied to confirm VZV infection in cell culture, to visualize glycoprotein expression in infected monolayers by immunofluorescence, and to characterize gE processing in western blot separations of viral lysates.

Store refrigerated upon receipt; aliquotting is recommended to limit freeze-thaw cycles and preserve binding activity over multiple experiments.