Anti-Varicella-Zoster Virus (VZV-gB) Antibody

For research targeting Varicella-Zoster Virus (VZV), glycoprotein B (gB) is one of the most immunodominant envelope proteins, playing a central role in viral entry into host cells and cell-to-cell spread across mucosal and neural tissue. This monoclonal reagent from Antibodies.com is raised in mouse, cloned from the IgG1(k) isotype, and supplied as a purified, unconjugated antibody at 100 µg per vial.

It is validated for ELISA and immunofluorescence assay (IFA) workflows, making it useful for qualitative detection of VZV antigens in infected cell cultures, fixed tissue sections, and viral lysate preparations. Researchers apply VZV-gB specific antibodies to investigate viral tropism, study glycoprotein-mediated fusion mechanisms, distinguish VZV from other herpesviruses in co-infection models, and support serological assay development.

The unconjugated format allows flexible pairing with custom fluorophores, biotin, or horseradish peroxidase depending on the detection chemistry required. Store aliquots frozen at -20°C, avoid repeated freeze-thaw cycles, and protect from light when working with labelled derivatives. Brief centrifugation before opening the vial is recommended to recover the full antibody content.