Anti-VANGL2 Antibody

Within the Wnt/planar cell polarity (PCP) pathway, Vang-like protein 2 (VANGL2) is the four-pass transmembrane scaffold that drives convergent extension and neural tube closure, and Antibodies.com supplies this 100 µL rabbit polyclonal antibody to detect it on western blot and immunohistochemistry. Unconjugated and reactive against human, mouse, and rat samples, the polyclonal reagent supports developmental biology, stem cell, and cancer research workflows that need to localize endogenous VANGL2, follow hair follicle and inner-ear hair cell patterning, or screen for defects in oriented cell division. Researchers studying neural tube defects use the antibody in IHC and WB to map PCP-pathway activity across embryonic and adult tissue and to dissect upstream regulators such as WNT5A, FZD3, and Dishevelled family members.