Anti-VAMP2 Antibody

This rabbit polyclonal antibody from Antibodies.com targets VAMP2, a 13 kDa SNARE protein anchored in synaptic vesicle membranes that mediates calcium-triggered fusion with the presynaptic plasma membrane during neurotransmitter release. Raised in rabbit and supplied as 100 ul of a 1 mg/ml stock in PBS with 0.1% sodium azide and 50% glycerol, the reagent is unconjugated and validated for Western blot and immunohistochemistry on human, mouse, and rat samples. VAMP2 (synaptobrevin-2) is a core component of the SNARE complex, and researchers use this reagent to map synaptic vesicle pools, quantify exocytotic machinery in neuronal cultures, and probe changes in synaptic protein abundance in models of neurodegeneration, stroke, and metabolic disease. The polyclonal format increases the likelihood of recognising VAMP2 across multiple epitopes, which is useful when probing tissue lysates where the protein may be partially cleaved or present in low abundance. Aliquot on first use and store at -20 degrees C to preserve activity; the glycerol-containing buffer protects against freeze-thaw damage, and the sodium azide addition prevents microbial contamination of working dilutions. Each vial ships ready to dilute for immunoblot or chromogenic IHC workflows, and the unconjugated format lets end users couple the antibody to their preferred fluorophore or enzyme label.