Anti-UV excision repair protein RAD23 homolog A Antibody

This polyclonal antibody from Antibodies.com targets UV excision repair protein RAD23 homolog A, a human DNA damage response factor that participates in the nucleotide excision repair (NER) pathway. RAD23A recognizes bulky UV-induced DNA adducts in cooperation with the XPC complex and shuttles ubiquitinated substrates to the proteasome via its UBA and UBL domains, making it a useful marker in studies of genome stability, UV photobiology, and ubiquitin-proteasome crosstalk.

Raised in rabbit and supplied unconjugated at 100 µg per vial, the reagent is validated for Western blot and immunohistochemistry applications on human samples. The polyclonal format yields multi-epitope recognition of the target, while the unconjugated conjugate leaves secondary reporter choice to the user, supporting both chemiluminescent immunoblotting and chromogenic or fluorescent staining of fixed tissue. Researchers working on skin biology, photodamage, xeroderma pigmentosum models, and proteasome shuttle mechanisms routinely profile RAD23A expression by WB and IHC using antibodies of this specificity.

Aliquot upon receipt and store refrigerated to preserve activity across the shelf life of the preparation.