Anti-USP7 Antibody

This rabbit polyclonal IgG reagent from Antibodies.com detects endogenous USP7 (also called HAUSP), a ubiquitin-specific deubiquitinating enzyme that governs protein stability by removing ubiquitin chains from substrates such as Mdm2, p53, and several histone targets. The unconjugated antibody was raised in rabbit against recombinant human USP7 and purified by affinity chromatography using the immunogen, yielding a reagent that recognizes total USP7 protein across both human and mouse samples for cross-species studies. It is validated for western blot and immunohistochemistry workflows, supporting oncology, virology, DNA damage response, and epigenetic research programs that interrogate USP7-mediated deubiquitination and p53 pathway dynamics. The reagent ships as a 100 µl vial of polyclonal antiserum formulated in PBS buffer (pH 7.4) containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol, with the unconjugated format allowing flexible pairing with user-selected secondary antibodies and detection chemistries. Upon arrival, aliquot the reagent and store at -20°C, avoiding repeated freeze-thaw cycles to preserve binding activity across multiple experiments.