Anti-USP28 Antibody

The USP28 (Ubiquitin Specific Peptidase 28) target is a cysteine-dependent deubiquitinating enzyme that belongs to the ubiquitin-specific protease (USP) family. This unconjugated rabbit polyclonal antibody is supplied by Antibodies.com at a 50 µl volume and is validated for Western blot detection of endogenous USP28 in human and mouse samples.

USP28 plays a documented role in the DNA damage response pathway, where it stabilizes key substrates including Chk2, 53BP1, and c-Myc through deubiquitination. The reagent is raised in rabbit, has an IgG isotype, and is supplied unconjugated to allow flexible secondary antibody pairing in standard immunoblotting workflows. Investigators studying oncogenic signaling, genomic instability, and post-translational modification pathways use this antibody to probe USP28 expression across cancer cell lines and tissue lysates.

For best results, follow standard polyclonal antibody storage conditions and minimize freeze-thaw cycles to preserve reactivity across multiple experiments.