Anti-USP25 Antibody

The Antibodies.com rabbit polyclonal reagent targets USP25, a member of the ubiquitin-specific protease family that removes ubiquitin modifications from substrate proteins to regulate their stability, activity, and intracellular trafficking. USP25 is widely expressed across human, mouse, and rat tissues and has been investigated for its role in modulating innate immune signaling through TRAF3 and TRAF6, shaping type I interferon responses, and contributing to inflammatory pathway regulation. The antibody is supplied as a 100 µL unconjugated IgG preparation validated for western blot, immunohistochemistry, and immunoprecipitation workflows. Researchers have applied anti-USP25 antibodies to studies of viral innate immunity, deubiquitination in cancer cell proliferation, and crosstalk between the ubiquitin-proteasome system and inflammatory signaling networks. The polyclonal format enables recognition of multiple epitopes on the target protein, which is useful when probing samples from different species or experimental systems. For reliable performance, refrigerate the vial at 4°C and minimize freeze-thaw cycles to preserve binding activity. This research-use-only reagent is suited to cell biology, immunology, and oncology investigations where USP25 function is being characterized.