Anti-USP21 Antibody

Raised in rabbit and validated for Western blot and immunohistochemistry, this unconjugated polyclonal IgG reagent from Antibodies.com targets USP21, a deubiquitinating enzyme that modulates histone H2A ubiquitination and influences DNA damage response, chromatin regulation, and innate immune signaling. The antibody is reactive against human and mouse samples and is supplied as 100 µl of stock, suitable for probing endogenous USP21 in cell lysates, tissue homogenates, and formalin-fixed paraffin-embedded sections. Its polyclonal format provides broader epitope coverage, which is helpful when studying protein isoforms or post-translational modifications. Because the reagent is unconjugated, investigators can pair it with HRP-, fluorophore-, or biotin-labeled secondary antibodies depending on the chosen imaging or detection platform. Recommended storage is refrigerated at 4 °C; for longer-term use, aliquot to limit freeze-thaw cycles. Researchers in oncology, epigenetics, and immune signaling will find this reagent relevant for studies of hepatocellular carcinoma, STING-mediated innate immunity, and transcription factor stability governed by ubiquitin turnover.