Anti-USP15 Antibody

Ubiquitin Specific Peptidase 15 (USP15) is a member of the USP family of cysteine proteases that removes ubiquitin from substrate proteins, and this rabbit polyclonal primary antibody from Antibodies.com is raised against the human target for research applications in cell signaling, DNA damage response, and cancer biology.

Validated for Western blot, immunohistochemistry, and immunofluorescence workflows, the unconjugated reagent enables detection of endogenous USP15 in human cells and tissue sections. Its polyclonal design allows recognition of multiple epitopes on the target, supporting studies of deubiquitinase-mediated regulation in pathways such as the DNA damage response, TGF-β signaling, and innate immune control. Researchers commonly apply this antibody to investigate USP15 substrate turnover, subcellular localization, and its emerging role as a candidate therapeutic target in oncology.

The antibody is supplied as 100 µl of liquid in a vial, unconjugated and free of reporter conjugates, so it can be paired with the researcher's preferred HRP-, biotin-, or fluorophore-conjugated secondary reagents. Host species is rabbit, clonality is polyclonal, conjugate is unconjugated, and reactivity has been confirmed for human samples. For handling, refrigerate on receipt, aliquot to limit repeated freeze-thaw cycles, and protect from light when working with fluorescent secondaries downstream to preserve activity across the working shelf life of the product.