Anti-USO1 Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com targets USO1 (also known as p115 or TAP), a peripheral Golgi-associated protein essential for vesicle tethering and ER-to-Golgi trafficking. The IgG reagent is supplied at 200 µl and is validated for western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) applications, with demonstrated reactivity against human and mouse samples.

USO1 functions as a tethering factor that mediates docking of COPII and COPI transport vesicles to Golgi cisternae through interactions with Rab1, GM130, and giantin. Researchers investigating Golgi architecture, secretory pathway dynamics, and vesicular transport mechanisms rely on this antibody to study membrane trafficking, subcellular localization, and the regulation of vesicle fusion events. The reagent is also used in studies exploring the role of USO1 dysregulation in cancer cell migration, neurodegenerative disease models, and cellular stress responses involving the secretory pathway.

Provided as a polyclonal reagent in an unconjugated format, the antibody pairs with secondary antibodies matched to rabbit IgG for flexible assay design. The 200 µl volume supports multiple western blot, IHC, and IF experiments in standard chromogenic and fluorescence detection workflows.