Anti-UNC13 (C. elegans)-like Antibody

The UNC13 protein family includes key regulators of synaptic vesicle priming and neurotransmitter release, with mammalian homologs (Munc13-1 through Munc13-4) sharing conserved C1 and C2 domains essential for calcium-triggered vesicle fusion at presynaptic terminals.

This polyclonal reagent from Antibodies.com is raised in rabbit and targets the UNC13-like sequence, supporting neuroscience and synaptic biology research applications. The antibody is validated for Western blot and immunohistochemistry workflows on human samples, enabling investigators to examine endogenous protein expression in cell lysates and fixed tissue sections.

Supplied unconjugated in a 100 µl volume, the reagent offers flexibility for downstream detection chemistry and custom labeling strategies. As a research-use-only primary antibody, it supports studies of synaptic transmission, neuronal signaling pathways, and the potential involvement of UNC13 in neurodevelopmental or neurodegenerative processes.