Anti-UKHC Antibody

UKHC (Ubiquitous Kinesin Heavy Chain), also designated KIF5B, is a microtubule-based motor protein responsible for anterograde organelle transport along axonal and dendritic microtubules in human cells. Antibodies.com supplies this unconjugated rabbit polyclonal reagent as a 100 µl liquid aliquot raised against the heavy chain of human kinesin-1, validated for western blot (WB) and immunohistochemistry (IHC) applications. The polyclonal antibody recognizes multiple epitopes across the heavy chain, supporting detection of full-length and partially processed forms of the motor in lysates and fixed tissue sections prepared from cultured mammalian cells. Investigators studying vesicle trafficking, mitotic spindle organization, and cytoskeletal motor function use UKHC/KIF5B probes to map subcellular localization and to monitor expression changes in neurodegeneration, cancer cell migration, and viral trafficking studies, since KIF5B participates in dynein-kinesin coordination during endosomal sorting. The product is provided in a single vial, should be kept refrigerated between uses, and aliquoted and frozen if longer-term storage is required to limit freeze-thaw loss of titer. Reactive against human UKHC in tested applications.