Anti-UGT1A4 Antibody

The target UGT1A4 is a UDP-glucuronosyltransferase enzyme of the phase II drug metabolism pathway, predominantly expressed in hepatic tissue. Antibodies.com provides this affinity-purified reagent as an unconjugated primary antibody in a 100 µl vial, ready for direct incorporation into immunodetection workflows without additional conjugation steps.

Validation has been demonstrated for Western blot (WB) and immunohistochemistry (IHC) applications. Common research uses include profiling hepatic glucuronidation capacity, dissecting drug clearance pathways for clinically relevant substrates such as lamotrigine, olanzapine, and tacrolimus, and distinguishing expression of UGT1A4 from other isoforms within the UGT1A gene cluster on chromosome 2q37.

Because the antibody is unconjugated, investigators retain freedom to pair it with their preferred secondary reagent and detection chemistry, supporting chromogenic, chemiluminescent, and fluorescence-based readouts across fixed tissue sections and whole-cell lysates. Aliquot upon arrival and store frozen to minimize freeze-thaw cycles. Intended for research use only, not for diagnostic or therapeutic procedures.