Anti-UBE4B Antibody

Raised in Rabbit against the UBE4B target, this unconjugated polyclonal antibody from Antibodies.com supports western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) workflows on human samples. UBE4B is a U-box-containing E3 ubiquitin ligase that catalyzes multi-ubiquitin chain assembly on substrates destined for proteasomal degradation, and it participates in the DNA damage response through polyubiquitination of p53. The protein has been investigated in the context of certain malignancies and in pathways controlling cell-cycle checkpoint signaling. Supplied at 100 µL, the reagent provides flexibility for downstream secondary antibody selection and choice of detection chemistry. For best results, store aliquots at -20 degrees C, avoid repeated freeze-thaw cycles, and protect from light. The polyclonal antibody mixture recognizes multiple epitopes on the target, increasing the likelihood of robust signal across experimental conditions.