Anti-UBE3C Antibody

Raised in rabbit and affinity-purified, this polyclonal IgG reagent from Antibodies.com is designed to detect endogenous levels of the human UBE3C ubiquitin-protein ligase, also referenced in the literature as HectH2, RAUL, KIAA0010, or KIAA10. The unconjugated antibody is supplied at a working concentration of 1 mg/ml in a 50 µl vial, formulated for direct use in standard immunodetection workflows. It has been validated for Western blotting (WB) and immunofluorescence/immunocytochemistry (IF) applications on human samples, making it suitable for studies of protein expression, subcellular localization, and pathway analysis involving this HECT-type E3 ubiquitin ligase, which runs at approximately 124 kDa. The polyclonal format provides multi-epitope recognition of the target, while the unconjugated state allows researchers to pair the reagent with their preferred secondary antibody or fluorescent label. With an IgG isotype background and a recommended storage condition of -20 °C for continuous use, with repeated freeze-thaw cycles to be avoided, the product is intended for research use only and is not approved for diagnostic or therapeutic applications. Investigators studying E3 ligase biology, ubiquitination cascades, or RTA-associated ubiquitin ligase activity will find this reagent a reliable tool for consistent performance in cell-based immunostaining and lysate-based Western blot assays.