Anti-UBE2V2 Antibody

This polyclonal antibody targets UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2), a catalytically inactive E2 variant that pairs with UBE2N/Ubc13 to assemble K63-linked polyubiquitin chains during error-free post-replication DNA repair and NF-κB signaling. Produced by Antibodies.com as an unconjugated rabbit IgG preparation, the reagent is supplied at 1 mg/ml in a PBS buffer containing 0.1% sodium azide and 50% glycerol as a cryoprotectant, in a 100 µl vial format that supports multiple experimental runs.

The antibody is validated for Western blot analysis of whole-cell lysates, immunohistochemistry on paraformaldehyde-fixed tissue sections, and immunofluorescence microscopy for subcellular localization. Confirmed reactivity with human, mouse, and rat samples lets investigators move between cell line work and rodent tissue validation within the same reagent lot, and the unconjugated format allows pairing with a researcher-selected reporter dye or enzyme for custom detection panels.

For best stability, keep the vial refrigerated and protect from light, and minimize freeze-thaw cycles; aliquotting into smaller working volumes is advisable when the antibody will be used intermittently. The preparation is intended for research use only and is not approved for diagnostic procedures.