Anti-UBE2V1 Antibody

Targeting the UBE2V1 ubiquitin-conjugating enzyme variant, this polyclonal rabbit reagent from Antibodies.com is supplied as 100 µl of a 1 mg/ml stock in PBS containing 0.1% sodium azide and 50% glycerol. UBE2V1 partners with UBE2N/Ubc13 to assemble K63-linked polyubiquitin chains during DNA double-strand break repair and the error-free branch of post-replication repair, making this antibody a useful tool for studies of genome stability, NF-κB signalling through the TRAF6 ubiquitin ligase complex, and altered UBE2V1 expression in tumour cell lines. The unconjugated reagent is validated for Western blot and immunohistochemistry on human and mouse samples, including formalin-fixed paraffin-embedded sections used in IHC. For best stability, store the vial frozen at -20 °C, protect from light, and aliquot on first use to limit repeated freeze-thaw cycles of the glycerol stock.