Anti-UBE2J2 Antibody

UBE2J2 is an ER-anchored ubiquitin-conjugating enzyme that participates in ER-associated degradation (ERAD) and the ubiquitin-proteasome system, where it partners with E3 ligases such as gp78/AMFR to retrotranslocate misfolded substrates including CFTR. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against UBE2J2 and supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, shipped as a 100 µl aliquot that supports several immunoblots or staining runs. It has been validated for western blot, immunohistochemistry, and immunofluorescence, and it cross-reacts with human, mouse, and rat samples, enabling comparative work across mammalian model systems. Researchers studying cystic fibrosis transmembrane conductance regulator (CFTR) quality control, endoplasmic reticulum stress, and membrane-bound ubiquitin ligase cascades can apply this reagent to detect endogenous UBE2J2 in cell lysates, fixed tissue sections, and cultured cells.