Anti-UBE2D1 Antibody

Raised in rabbit against ubiquitin-conjugating enzyme E2 D1 (also known as UBC5A), this unconjugated polyclonal reagent from Antibodies.com supports studies of E2 enzyme activity in the ubiquitin-proteasome system. UBE2D1 partners with multiple E3 ligases to mediate substrate ubiquitination in pathways that control cell cycle progression, p53 turnover, NF-κB signaling, and the DNA damage response, making the target relevant to research on protein homeostasis and post-translational regulation.

Supplied as 100 µL of unconjugated antisera, the antibody is validated for Western blot (WB) and immunohistochemistry (IHC) workflows and shows reactivity with human, mouse, and rat samples. The polyclonal format covers multiple epitopes across the target, useful when detecting endogenous UBE2D1 in cell lysates or assessing its tissue distribution in fixed sections. Researchers commonly apply this reagent to investigate E2 enzyme function, E3 ligase partnerships, and ubiquitin-dependent signaling cascades.

For storage, refrigerate the vial upon arrival; for longer-term use, aliquot and freeze, and avoid repeated freeze-thaw cycles. Protect from light and handle with standard laboratory precautions. Intended for research use only.