Anti-UBE2C Antibody

Raised in rabbit and supplied unconjugated at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, this polyclonal reagent from Antibodies.com detects ubiquitin-conjugating enzyme E2C, an E2 ligase that drives mitotic progression through targeted proteolysis of securin and cyclin B via the anaphase-promoting complex. Validated for western blot, immunohistochemistry, and immunofluorescence workflows, it shows reactivity across human, mouse, and rat sample types.

The 100 µl format is aliquoted for working dilution convenience in research settings focused on cell cycle biology, spindle assembly checkpoint analysis, and oncology, where aberrant UBE2C overexpression is frequently examined as a proliferation biomarker in tumor tissues. Investigators studying APC/C-dependent ubiquitination, chromosomal segregation fidelity, or cancer cell growth kinetics will find the antibody applicable to both qualitative and semi-quantitative assays, including western blot band quantification and immunofluorescence imaging of dividing cells.

Aliquot upon receipt to limit freeze-thaw cycles and dilute according to your established protocol for each application.