Anti-UBAP2L Antibody

UBAP2L is a ubiquitin-associated protein that participates in stress granule assembly and RNA metabolism, with documented roles in translational regulation and cancer cell proliferation. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against UBAP2L and validated for Western blot and immunocytochemistry workflows across Human, Mouse, and Rat samples. The antibody is supplied as 100 µl of a 1 mg/ml stock solution in phosphate buffered saline with 0.05% sodium azide at approximately pH 7.2, and is intended for research use only in academic and translational laboratories studying post-translational modification pathways, RNA-binding protein networks, or stress response biology.

For Western blot, the polyclonal format offers broader epitope coverage useful when probing full-length UBAP2L in cell lysates, while immunocytochemistry compatibility enables visualisation of cytoplasmic stress granule localisation under conditions such as sodium arsenite or sorbitol-induced stress. Sodium azide at 0.05% permits short-term refrigerated storage; long-term stability is improved by aliquoting the solution at sub-zero temperatures, and researchers should avoid repeated freeze-thaw cycles to preserve antibody activity. The unconjugated format allows pairing with user-preferred HRP, Alexa Fluor, or biotin secondary reagents depending on detection needs.

Quality-controlled lots are evaluated on relevant cell lines expressing endogenous UBAP2L, supporting reproducible signal in both basal and stress-induced conditions. Researchers investigating oncogenic signalling pathways, mRNA surveillance mechanisms, or granule-associated disease models will find the Human, Mouse, and Rat reactivity profile broadly applicable to standard in vitro and in vivo experimental systems.