Anti-UBA6 Antibody

A rabbit polyclonal primary antibody from Antibodies.com targets UBA6, the ubiquitin-like modifier-activating enzyme 6 that initiates ubiquitin conjugation through a parallel activation pathway distinct from UBA1 and also charges the ubiquitin-like modifier FAT10. Supplied as 100 µl at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the unconjugated reagent is validated for Western blot and immunohistochemistry across human, mouse, and rat samples. The 50% glycerol formulation permits storage at -20°C with minimal freeze-thaw cycling. UBA6, also designated E1-L2 or UBE1L2, runs as a ~112 kDa protein, supporting detection by immunoblotting in lysates from tissues and cultured cells. Researchers studying FAT10-dependent proteasomal degradation, ubiquitin homeostasis, and mitotic regulation use this reagent to profile endogenous UBA6 expression patterns. The polyclonal format broadens epitope coverage across the target, useful when probing conserved regions in rodent and human specimens.