Anti-U2SURP Antibody

This polyclonal reagent from Antibodies.com is a rabbit IgG antibody raised against U2SURP (also known as SR140), a SURP-domain-containing splicing factor that associates with the U2 small nuclear ribonucleoprotein complex during spliceosome assembly. The unconjugated antibody is supplied as a 50 µl vial and has been validated for Western blot and immunohistochemistry across human, mouse, and rat samples, supporting studies of alternative splicing regulation and pre-mRNA processing in cell and tissue lysates. U2SURP participates in early spliceosome recognition of the branch point sequence, and researchers use this reagent to investigate its expression, subcellular localization, and role in transcriptional regulation, developmental biology, and disease models where splicing fidelity is altered. For best results, store the vial at -20 °C in working aliquots to limit freeze-thaw cycles, and dilute according to your Western blot or IHC protocol.