Anti-U2SURP Antibody

U2SURP, also called SR140, is a serine/arginine-rich splicing factor that functions as a core component of the U2 small nuclear ribonucleoprotein (snRNP) and contributes to early spliceosome assembly and alternative splicing regulation in the nucleus. This unconjugated Rabbit polyclonal IgG antibody from Antibodies.com was raised against U2SURP and validated for western blot and immunohistochemistry on human, mouse, and rat specimens.

The reagent is supplied as 200 µL of liquid antiserum in a single vial, ready for dilution into standard blocking buffers. Researchers use it to probe U2SURP expression across cancer cell lines, to study nuclear speckle localization, and to investigate splicing dysregulation in neurodegeneration and mRNA processing studies. The antibody is also compatible with co-immunoprecipitation workflows for mapping SR140 protein-protein interactions.

For handling, aliquot upon first use and store at 4 °C for short-term stability or -20 °C for long-term preservation, avoiding repeated freeze-thaw cycles to maintain titer.