Anti-U2AF1L4 Antibody

Raised in rabbit against the U2AF1L4 splicing factor, this polyclonal unconjugated antibody from Antibodies.com is supplied as a 100 µl aliquot at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol. U2AF1L4 (U2 small nuclear RNA auxiliary factor 1-like 4) participates in pre-mRNA splicing as part of the spliceosome machinery, and antibodies raised against it are commonly used to study RNA processing, spliceosome assembly, and post-transcriptional gene regulation in human cells and tissues.

The reagent is validated for western blot, immunohistochemistry, and immunofluorescence applications, with reactivity reported against human samples. The polyclonal format recognises multiple epitopes on U2AF1L4, which can improve tolerance for minor conformational variation between samples compared with monoclonal reagents. The glycerol-containing formulation supports cold storage and limits freeze-thaw stress by allowing convenient withdrawal of working aliquots.

Researchers commonly deploy this reagent when characterising U2AF1L4 expression across tissues, examining its nuclear localisation by immunofluorescence, or probing its involvement in alternative splicing programmes. The unconjugated format leaves open the choice of secondary detection, allowing peroxidase, fluorophore, or biotin-based readouts to be paired with the primary antibody. As with any azide-containing formulation, the solution should be handled with appropriate laboratory safety practice and protected from light during prolonged storage.