Anti-U1-C Antibody [4H12]

The 4H12 clone targets the U1-C subunit (also called SNRPC) of the U1 small nuclear ribonucleoprotein particle, a core component of the spliceosome that recognises the 5' splice site during pre-mRNA processing. Antibodies.com supplies this reagent as a 100 µg liquid preparation in IgG2a format, unconjugated, raised in rat.

Validated for western blot, immunocytochemistry, immunohistochemistry on frozen tissue sections, and ELISA, the antibody cross-reacts with human, monkey, and mouse samples, supporting comparative studies of splicing factor distribution and snRNP assembly.

For best stability, store the vial at -20°C and avoid repeated freeze-thaw cycles by aliquoting on first use.