Anti-Tyrosine Hydroxylase Antibody [N37]

The Anti-Tyrosine Hydroxylase Antibody [N37] from Antibodies.com is a mouse monoclonal IgG1 antibody that specifically detects tyrosine hydroxylase (TH), the rate-limiting enzyme catalyzing the conversion of L-tyrosine to L-DOPA in the catecholamine biosynthesis pathway. This unconjugated reagent is widely used in neuroscience research as a selective marker for catecholaminergic neurons, including dopaminergic cells of the substantia nigra and ventral tegmental area, supporting studies in Parkinson's disease, addiction, and neurodevelopment.

Validated for western blot, IHC-P, and IHC-Fr applications, the antibody cross-reacts with human, mouse, rat, and rabbit samples, enabling translational work across rodent models and human tissue. The N37 clone detects TH-expressing neurons in regions such as the locus coeruleus and adrenal medulla chromaffin cells, providing a reliable tool for studying monoaminergic pathways. Supplied as 100 µg in a vial, the liquid formulation should be stored in frozen aliquots to limit freeze-thaw cycles and preserve antibody activity across multiple experiments.