Anti-TXNRD2 Antibody

Manufactured by Antibodies.com, this rabbit polyclonal reagent is raised against human thioredoxin reductase 2 (TXNRD2), a mitochondrial selenoenzyme also referenced by the synonyms TRXR2, TR3, TR-beta, SelZ and Selenoprotein Z. The antibody is purified by affinity chromatography using the immunogen and is supplied unconjugated at 1.0 mg/mL in a phosphate-buffered saline formulation (pH 7.4, 150 mM NaCl) containing 0.02% sodium azide and 50% glycerol as a cryoprotectant. It is offered in a 50 µl volume and is validated for Western blot (WB) and immunohistochemistry (IHC) applications, with demonstrated staining on paraffin-embedded rat kidney tissue at a 1:200 dilution. The antibody specifically detects endogenous levels of total TXNRD2 protein and has been verified to react with Human and Mouse samples, making it suitable for studies in cell biology, redox biology and mitochondrial function across a range of mammalian model systems. As a research-use-only reagent, it is intended for laboratory applications such as western blotting of cell and tissue lysates and IHC-based localization of TXNRD2 in fixed sections, providing a reliable tool for investigators examining thioredoxin-mediated antioxidant pathways. The polyclonal nature of the reagent means it recognizes multiple epitopes on the TXNRD2 target, which can be advantageous for detecting the protein under varying expression conditions and across different sample preparations.