Anti-TXNDC5 Antibody

Raised in rabbit against the human endoplasmic-reticulum protein TXNDC5, this unconjugated IgG polyclonal reagent is supplied by Antibodies.com as 100 µl of antiserum prepared for western blot detection of thioredoxin domain-containing protein 5 in cell and tissue lysates. The antibody recognizes a native PDI-family member involved in oxidative protein folding and ER redox homeostasis, supporting studies of disulfide bond formation, unfolded protein response signaling, and stress-pathway analysis in human-derived samples.

Because the reagent is unconjugated, it pairs flexibly with HRP-, biotin-, or fluorophore-tagged secondary antibodies matched to a chosen chemiluminescence or fluorescence imaging platform. Researchers commonly deploy it at empirically optimized dilution on standard SDS-PAGE gels, transferring resolved bands to nitrocellulose or PVDF membranes and developing with ECL substrates to visualize the target at its expected molecular weight. Each 100 µl vial supports multiple blotting experiments, with dilution factor and membrane size determining the number of runs. Storage at -20 °C in small aliquots is recommended to limit freeze-thaw cycles and preserve titer for longitudinal TXNDC5 expression studies.