Anti-Twist1 Antibody - Identical to Thermo (PA5-49688)

The Antibodies.com anti-Twist1 polyclonal antibody is raised in rabbit and supplied as an unconjugated reagent in a 100 µl vial. Twist1 (Twist-related protein 1, also called bHLHa38) is a basic helix-loop-helix transcription factor best known for driving epithelial-mesenchymal transition (EMT), mesoderm specification during embryogenesis, and metastatic programs in carcinoma cells; heterozygous loss-of-function mutations in TWIST1 cause Saethre-Chotzen syndrome, a craniosynostosis disorder. This reagent was validated for Western blot (WB) and immunohistochemistry (IHC) and recognizes the Twist1 protein in human, mouse, and rat samples, supporting cross-species work in developmental biology, stem cell research, and oncology workflows such as tumor invasion and EMT marker studies. The host species is rabbit, the clonality is polyclonal, and the antibody is provided without a fluorophore or enzyme label so it can be paired with a secondary reagent of the researcher's choice for chemiluminescent WB or chromogenic IHC detection. The product is positioned as sequence-identical to a widely used Thermo Fisher reference reagent, giving labs a consistent anti-Twist1 reagent for validation studies, pathway analysis (notably the Twist1/Snail/E-cadherin axis), and confirmation experiments alongside existing in-house antibodies.