Anti-TWIST1 Antibody

TWIST1 is a basic helix-loop-helix transcription factor central to embryonic morphogenesis, mesenchymal cell fate decisions, and epithelial-mesenchymal transition (EMT). Aberrant TWIST1 expression is widely studied in metastatic carcinoma research, craniofacial developmental disorders such as Saethre-Chotzen syndrome, and stem cell reprogramming workflows.

This rabbit polyclonal reagent from Antibodies.com is raised against the human TWIST1 protein and supplied as 50 µl of unconjugated IgG in a single-use vial, validated for Western blot detection of TWIST1 in lysates from human, mouse, and rat samples. Researchers commonly apply it to track TWIST1 induction during EMT modeling, characterize disease-associated mutations, or profile tumor cell lines with elevated Twist1 levels.

Aliquot the reagent upon arrival to limit repeated freeze-thaw cycles, store refrigerated, and protect the vial from light to preserve antibody activity. The polyclonal format provides recognition of multiple epitopes across the TWIST1 protein, supporting reproducible detection in whole-cell or nuclear extracts when paired with HRP- or fluorophore-conjugated secondary reagents.