Anti-TWIST1 Antibody

This rabbit polyclonal reagent from Antibodies.com targets TWIST1, a basic helix-loop-helix transcription factor central to mesoderm specification, cranial suture closure, and the epithelial-mesenchymal transition program that underlies both normal development and tumour cell dissemination. Raised in rabbit and purified as an IgG preparation supplied unconjugated in a 200 µl vial, the antibody is validated for Western blot detection of the ~21 kDa TWIST1 protein in lysates derived from human, mouse, and rat samples. Researchers studying craniofacial morphogenesis, neural crest delamination, or the metastatic behaviour of carcinomas commonly use this reagent to follow TWIST1 expression changes in response to pathway perturbations or hypoxia, and to compare endogenous levels across cell-line panels that model EMT. The polyclonal format provides broader epitope coverage than monoclonal alternatives when working with mutant or post-translationally modified TWIST1 species, and the unconjugated presentation supports flexible secondary antibody pairing for fluorescence or chemiluminescence chemistries downstream of the primary incubation step.