Anti-TWF2 Antibody

TWF2 (Twinfilin-2) is a member of the twinfilin family of actin monomer-binding proteins that contributes to cytoskeletal regulation and cell motility. This rabbit polyclonal antibody from Antibodies.com is raised against the human TWF2 target and is supplied as 100 µl of unconjugated antisera for western blot (WB) and immunohistochemistry (IHC) workflows.

TWF2 contains two ADF/cofilin-like domains and sequesters actin monomers, regulating actin filament turnover at the leading edge of migrating cells. The antibody has been validated for detection in human, mouse, and rat samples, supporting comparative studies across model organisms.

Recommended applications include immunoblotting of cell and tissue lysates to probe TWF2 expression levels, and immunohistochemistry on fixed sections to localize TWF2 in tissues such as brain, kidney, and liver. Store the vial at -20 °C in aliquots to avoid repeated freeze-thaw cycles, and protect from light when handling the unconjugated stock. This polyclonal reagent offers broader epitope coverage than monoclonal alternatives for detecting multiple TWF2 isoforms.